Thursday, January 31, 2013

Will Tennessee teachers have to out gay students?

A pending "don't say gay" bill could force K-12 educators to inform parents if their child is ? or may be ? gay

In 2011, Tennessee State Sen. Stacey Campfield (R) earned the ire of gay-rights supporters by authoring and championing a "don't say gay" bill, forbidding teachers to even mention homosexuality to kids from pre-kindergarten through eighth grade. The bill passed out of the relevant committees of both the state House and the Senate, but expired at the end of the legislative session in 2012. Well, "it's back," says Katie McDonough at Salon. "And it's awful," even worse than the previous version. Why? This time, Campfield added new language in the bill that "would require teachers to tell parents when students are ? or might be ? gay." Here's the relevant section of the bill:

The general assembly recognizes that certain subjects are particularly sensitive and are, therefore, best explained and discussed within the home. Because of its complex societal, scientific, psychological, and historical implications, human sexuality is one such subject. Human sexuality is best understood by children with sufficient maturity to grasp its complexity and implications. At grade levels pre-K through eight (pre-K-8), any such classroom instruction, course materials or other informational resources that are inconsistent with natural human reproduction shall be classified as inappropriate for the intended student audience and, therefore, shall be prohibited....

A school counselor, nurse, principal or assistant principal from counseling a student who is engaging in, or who may be at risk of engaging in, behavior injurious to the physical or mental health and well-being of the student or another person; provided, that wherever possible such counseling shall be done in consultation with the student's parents or legal guardians. Parents or legal guardians of students who receive such counseling shall be notified as soon as practicable that such counseling has occurred. [PDF]

What is Campfield thinking? Well first, unlike lawmakers in California, who banned the controversial gay "conversion" therapy on minors, says Salon's McDonough, Campfield is apparently a fan of the practice "('counseling' in the bill's nomenclature), in which psychologists and psychiatrists... try to change the recipient's sexual orientation." Many states require teachers to report "any signs of child being abused, depressed or suicidal" to parents or higher authorities, says Ilana Glazer at The Daily Beast, and?Campfield apparently believes that "being gay is so abnormal, it must be reported so that such behavior can be thwarted." Still:

This Tennessee bill, coupled with the recent Boy Scout debate seem to be part of a disturbing trend. While equality battles up until now have been about LGBT rights for adults, the debate has now shifted to a point where children are becoming collateral damage. [Daily Beast]

Campfield mostly "seems determined that his name will forever more be synonymous with the term 'gay-bashing,'" says Jackson Baker at the Memphis Flyer. That, and making a name for himself, period. It's hard to escape the fact that this new "don't say gay" bill actually does let you "say 'gay' if you must, but say it out of the hearing of the Regular Kids and in a way that isolates the suspected or known outliers and makes them squirm. Call it Tough Love. Call it The Cure." Luckily, "we will hazard here the prediction that Campfield's newest philippic against the state of gaydom will ultimately meet the fate of his first effort" ? death by inaction.

SEE MORE: 5 reasons the Boy Scouts might end its ban on gays

Let's hope so, says Annie-Rose Strasser at ThinkProgress. "Family rejection is a serious risk for LGBT youth," often leading to depression or suicide. And if this legislation does pass, plenty more gay kids will surely "face alienation, if not outright abandonment," and the state will be saddled with an epidemic of marginalized or homeless children.

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Source: http://news.yahoo.com/tennessee-teachers-gay-students-092200238.html

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Court looking at Station fire worker's comp fine | WPRI.com

WEST WARWICK, R.I. (WPRI) -- The state's Workers' Compensation Court wants to know why a penalty levied in the wake of the Station nightclub fire still has not been paid.

The court has scheduled a meeting for next Monday to find out why no action has been taken against former Station nightclub owners, Michael and Jeffrey Derderian, and their company, DERCO, LLC, on a penalty assessed more than eight-and-a-half years ago.

One hundred people, including four club employees, were killed Feb. 20, 2003 when the West Warwick club caught fire. Later that year, the Department of Labor fined the club owners and their company for failing to purchase workers' compensation insurance for their employees as required by law. In 2004, the state Workers' Compensation Court upheld the fine.

Our news partners, The Providence Journal , inquired as to why the more-than $1 million penalty against the Derderians' company had not been enforced or vacated.

The paper reported the penalty was appealed and put on hold several years ago.

The Department of Labor and Training, which is a party to the case, released a statement Tuesday regarding the inquiry.

"At present, the Department of Labor and Training believes that it followed standard procedures concerning any required notifications to the Workers' Compensation Court in the case of Michael and Jeffrey Derderian. However, the Department of Labor and Training and the Workers' Compensation Court are working together to investigate the matter further."

Source: http://www.wpri.com/dpp/news/local_news/west_bay/court-looking-at-station-fire-workers-comp-fine

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Wednesday, January 30, 2013

Next Apple iPad hits shelves next week VIDEO


The 128GB iPads will be available in Apple stores, the Apple Online store and ?select Apple Authorized Resellers.??

Apple Inc. says the latest incarnation of its fourth-generation iPad -- this one with double the storage of its current largest model -- will hit shelves on Feb. 5.

The step up to 128GB versions of the iPad is an incremental one for Apple (Nasdaq: AAPL), and one that seems aimed at enterprises and other users with large amounts of data, according to The Wall Street Journal?s Digits blog.

Prices will range from $799 for the Wi-Fi model to $929 for the Wi-Fi-plus-cellular model, according to Apple?s news release. The new versions will be available in the Apple Online store, Apple stores and ?select Apple Authorized Resellers.?

The Silicon Valley Business Journal posted a report about the dropping prices for Apple?s stock and some of its earlier product models -- and what that might mean for the Cupertino, Calif.-based tech giant. At the same time, several other news sources are showing leaked pictures of possible prototypes of the new iPad, iPad Mini and a ?budget? iPhone 5.

Apple Inc. has two stores in Orlando and one in Altamonte Springs.

Source: http://feeds.bizjournals.com/~r/bizj_orlando/~3/ZydGccBWDEg/next-apple-ipad-hits-shelves-next-week.html

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Mayor Jones shifting perspective to building the "best" Richmond

RICHMOND, VA (WWBT)- The state of Richmond is strong and growing stronger -??that's the message from Mayor Dwight Jones in his annual "State of the City" address Tuesday night.

Jones spoke to about a hundred people downtown at CenterStage. No huge groundbreaking proposals were announced, but Jones is shifting his perspective from "building a better Richmond," as we've heard him say over the last four years, to "building the best Richmond," in the year to come.

"We are building the best Richmond, because that is what you deserve, that is what I deserve, that is what our children deserve," said Jones.

How to get to that "best" Richmond is the focus,?building on the successes Mayor?Jones believes he's accomplished in the last four years. He is the first mayor under this form of government to have a second term in office, and he's set some lofty goals.

"It's time for us to redefine what 'possible' means. I want you to join me tonight in reinventing 'possible,'" said Jones.

Jones says the city can't reinvent "possible" without addressing the needs of its poorest citizens. He discussed poverty mitigation efforts, like improving transportation, revamping city housing projects, revitalizing neighborhoods, bringing more companies and jobs to the city and closing a funding gap for education.

"Richmond schools need to receive funding based on the city's poverty level. It compromises the very future of our city when we are measured as though we are as affluent as Chesterfield and Henrico," said Jones.

One topic that was not widely covered, despite the presence of the city's police chief and officers, is a decrease in crime statistics for the city.

"I think it's always important to point those things out," said City Council President Charles Samuels.?"I'm not a speech writer, so I can't really say what he should or shouldn't have touched on more, but I'll tell you what, it is on the minds of all of us on City Council."

The mayor hit on another hot button topic: baseball. He said the city is committed to building a new ballpark and keeping the Squirrels in the city. He did not, however, commit to a location, saying that decision will be based on financial analysis.

Copyright 2013 WWBT NBC12.? All rights reserved.

Source: http://thefan.nbc12.com/news/news/91034-mayor-jones-shifting-perspective-building-best-richmond

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Tuesday, January 29, 2013

Less invasive treatment is associated with improved survival in early stage breast cancer

Jan. 28, 2013 ? Patients with early stage breast cancer who were treated with lumpectomy plus radiation may have a better chance of survival compared with those who underwent mastectomy, according to Duke Medicine research.

The study, which appears online Jan. 28, 2013, in the journal Cancer, raises new questions as to the comparative effectiveness of breast-conserving therapies such as lumpectomy, where only the tumor and surrounding tissue is surgically removed.

"Our findings are observational but do suggest the possibility that women who were treated with less invasive surgery had improved survival compared to those treated with mastectomy for stage I or stage II breast cancer," said E. Shelley Hwang, M.D., MPH, chief of breast surgery at Duke Cancer Institute and the study's lead author.

Taking advantage of 14 years of data from the California Cancer Registry, a source of long-term outcome data for women diagnosed with and treated for breast cancer in California, the research team found improved survival to be associated with the less invasive treatment in all age groups, as well as those with both hormone-sensitive and hormone-resistant cancers. Women age 50 and older at diagnosis with hormone-sensitive tumors saw the largest benefit of choosing lumpectomy plus radiation: they were 13 percent less likely to die from breast cancer, and 19 percent less likely to die from any cause compared with those undergoing mastectomy.

Prior randomized trials have shown that when it comes to survival, lumpectomy with radiation is as effective as mastectomy in treating early stage breast cancer. As a result, the rate of women electing lumpectomy with radiation has climbed in the past few decades.

However, a recent trend has emerged with more early stage breast cancer patients, often younger women with very early cancers, opting for mastectomy. These women may perceive mastectomy to be more effective at eliminating early stage cancer and therefore reducing the anxiety accompanying long-term surveillance.

"Given the recent interest in mastectomy to treat early stage breast cancers despite the research supporting lumpectomy, our study sought to understand what was happening in the real world, how women receiving breast-conserving treatments were faring in the general population," Hwang said.

The team analyzed data from 112,154 women diagnosed with stage I or stage II breast cancer between 1990 and 2004, including 61,771 who received lumpectomy and radiation and 50,383 who had mastectomy without radiation.

The researchers looked at age and other demographic factors, along with tumor type and size to decipher whether each treatment had better outcomes for certain groups of women. Patients were followed on average for 9.2 years.

The researchers evaluated whether illnesses other than breast cancer, such as heart and respiratory disease, may have influenced whether women chose lumpectomy or mastectomy. Within three years of diagnosis, breast cancer patients who underwent lumpectomy and radiation had higher survival rates than those who chose mastectomy when all other illnesses were evaluated. This suggests that women choosing lumpectomy may have been generally healthier.

However, Hwang and her colleagues were surprised to also find that early stage breast cancer patients treated with breast-conserving treatment had a significantly better short-term survival rate from breast cancer than women who underwent mastectomy. A subset analysis limited to women with stage I cancer only showed consistent results.

"The hopeful message is that lumpectomy plus radiation was an effective alternative to mastectomy for early stage disease, regardless of age or tumor type," said Hwang. "Our study supports that even patients we thought might benefit less from localized treatment, like younger patients with hormone-resistant disease, can remain confident in lumpectomy as an equivalent and possibly better treatment option."

The authors emphasize that observational studies such as this one cannot establish causality between type of surgery and outcome and that longer follow up is needed. Nevertheless, this is a provocative observation that requires more research to understand whether patient factors that were not available for analysis might contribute to these observed survival differences.

In addition to Hwang, study authors include Daphne Y. Lichtensztajn, Scarlett Lin Gomez, and Christina A. Clarke of the Cancer Prevention Institute of California. Barbara Fowble of the University of California San Francisco Helen Diller Family Comprehensive Cancer Center also contributed to the research.

The study was supported by National Cancer Institute's Surveillance, Epidemiology and End Results Program (HHSN261201000140C) awarded to the Cancer Prevention Institute of California. The collection of cancer incidence data used in this study was supported by the California Department of Health Services.

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Story Source:

The above story is reprinted from materials provided by Duke Medicine.

Note: Materials may be edited for content and length. For further information, please contact the source cited above.


Journal Reference:

  1. E. Shelley Hwang, Daphne Y. Lichtensztajn, Scarlett Lin Gomez, Barbara Fowble, Christina A. Clarke. Survival after lumpectomy and mastectomy for early stage invasive breast cancer. Cancer, 2013; DOI: 10.1002/cncr.27795

Note: If no author is given, the source is cited instead.

Disclaimer: This article is not intended to provide medical advice, diagnosis or treatment. Views expressed here do not necessarily reflect those of ScienceDaily or its staff.

Source: http://feeds.sciencedaily.com/~r/sciencedaily/top_news/top_health/~3/bPMCfNocF50/130128104426.htm

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Safer way to vaccinate: Polymer film that gradually releases DNA coding for viral proteins may beat traditional vaccines

Jan. 28, 2013 ? Vaccines usually consist of inactivated viruses that prompt the immune system to remember the invader and launch a strong defense if it later encounters the real thing. However, this approach can be too risky with certain viruses, including HIV.

In recent years, many scientists have been exploring DNA as a potential alternative vaccine. About 20 years ago, DNA coding for viral proteins was found to induce strong immune responses in rodents, but so far, tests in humans have failed to duplicate that success.

In a paper appearing in the Jan. 27 online issue of Nature Materials, MIT researchers describe a new type of vaccine-delivery film that holds promise for improving the effectiveness of DNA vaccines. If such vaccines could be successfully delivered to humans, they could overcome not only the safety risks of using viruses to vaccinate against diseases such as HIV, but they would also be more stable, making it possible to ship and store them at room temperature.

This type of vaccine delivery would also eliminate the need to inject vaccines by syringe, says Darrell Irvine, an MIT professor of biological engineering and materials science and engineering. "You just apply the patch for a few minutes, take it off and it leaves behind these thin polymer films embedded in the skin," he says.

Irvine and Paula Hammond, the David H. Koch Professor in Engineering, are the senior authors of the Nature Materials paper. Both are members of MIT's David H. Koch Institute for Integrative Cancer Research. The lead author of the paper is Peter DeMuth, a graduate student in biological engineering.

Gradual vaccine delivery

Scientists have had some recent success delivering DNA vaccines to human patients using a technique called electroporation. This method requires first injecting the DNA under the skin, then using electrodes to create an electric field that opens small pores in the membranes of cells in the skin, allowing DNA to get inside. However, the process can be painful and give varying results, Irvine says.

"It's showing some promise but it's certainly not ideal and it's not something you could imagine in a global prophylactic vaccine setting, especially in resource-poor countries," he says.

Irvine and Hammond took a different approach to delivering DNA to the skin, creating a patch made of many layers of polymers embedded with the DNA vaccine. These polymer films are implanted under the skin using microneedles that penetrate about half a millimeter into the skin -- deep enough to deliver the DNA to immune cells in the epidermis, but not deep enough to cause pain in the nerve endings of the dermis.

Once under the skin, the films degrade as they come in contact with water, releasing the vaccine over days or weeks. As the film breaks apart, the DNA strands become tangled up with pieces of the polymer, which protect the DNA and help it get inside cells.

The researchers can control how much DNA gets delivered by tuning the number of polymer layers. They can also control the rate of delivery by altering how hydrophobic (water-fearing) the film is. DNA injected on its own is usually broken down very quickly, before the immune system can generate a memory response. When the DNA is released over time, the immune system has more time to interact with it, boosting the vaccine's effectiveness.

The polymer film also includes an adjuvant -- a molecule that helps to boost the immune response. In this case, the adjuvant consists of strands of RNA that resemble viral RNA, which provokes inflammation and recruits immune cells to the area.

The ability to provoke inflammation is one of the key advantages of the new delivery system, says Michele Kutzler, an assistant professor at Drexel University College of Medicine. Other benefits include targeting the wealth of immune cells in the skin, the use of a biodegradable delivery material, and the possibility of pain-free vaccine delivery, she says.

"It's an interesting approach that can be applied not just to delivery of DNA-based vaccine antigens, but other small molecules," says Kutzler, who was not part of the research team.

Eliciting immune responses

In tests with mice, the researchers found that the immune response induced by the DNA-delivering film was as good as or better than that achieved with electroporation.

To test whether the vaccine might provoke a response in primates, the researchers applied a polymer film carrying DNA that codes for proteins from the simian form of HIV to macaque skin samples cultured in the lab. In skin treated with the film, DNA was easily detectable, while DNA injected alone was quickly broken down.

"The hope is that that's an indication that this will translate to large animals and hopefully humans," Irvine says.

The researchers now plan to perform further tests in non-human primates before undertaking possible tests in humans. If successful, the vaccine-delivering patch could potentially be used to deliver vaccines for many different diseases, because the DNA sequence can be easily swapped out depending on the disease being targeted.

"If you're making a protein vaccine, every protein has its little quirks, and there are manufacturing issues that have to be solved to scale it up to humans. If you had a DNA platform, the DNA is going to behave the same no matter what antigen it's encoding," Irvine says.

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Story Source:

The above story is reprinted from materials provided by Massachusetts Institute of Technology. The original article was written by Anne Trafton.

Note: Materials may be edited for content and length. For further information, please contact the source cited above.


Journal Reference:

  1. Peter C. DeMuth, Younjin Min, Bonnie Huang, Joshua A. Kramer, Andrew D. Miller, Dan H. Barouch, Paula T. Hammond, Darrell J. Irvine. Polymer multilayer tattooing for enhanced DNA?vaccination. Nature Materials, 2013; DOI: 10.1038/nmat3550

Note: If no author is given, the source is cited instead.

Disclaimer: This article is not intended to provide medical advice, diagnosis or treatment. Views expressed here do not necessarily reflect those of ScienceDaily or its staff.

Source: http://feeds.sciencedaily.com/~r/sciencedaily/strange_science/~3/S-p9Fg4Dyxo/130128113922.htm

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Former trader charged with defrauding bailout fund

(AP) ? A former managing director of an investment bank was arrested Monday on charges he defrauded investment funds the Department of Treasury established in 2009 as part of the federal government's response to the financial crisis.

A federal grand jury in Connecticut returned a 16-count indictment charging 38-year-old Jesse C. Litvak of New York City with securities fraud, Troubled Asset Relief Program fraud and making false statements to the federal government, prosecutors said.

The indictment alleges Litvak, while a registered broker-dealer and managing director at Jefferies & Co., Inc. who worked on the company's trading floor in Stamford, engaged in a scheme to defraud customers on residential mortgage-backed securities trades.

"As alleged, the defendant defrauded six funds established by Treasury and funded principally with government bailout money," U.S. Attorney David Fein said. "Illegally profiting from a federal program designed to assist our nation in recovering from one of our worst economic crises is reprehensible."

Authorities say Litvak defrauded the six funds and private investment funds of more than $2 million. According to the indictment, Litvak was terminated from the company in 2011.

Litvak pleaded not guilty Monday in U.S. District Court in Bridgeport. His attorney, Patrick J. Smith, denied he defrauded anyone.

"These were principal transactions between sophisticated market participants," Smith said in a statement. "All of the profits that Jefferies earned on each trade were well within industry norms for the mortgage-backed bonds in this case. Jesse Litvak did not cheat anyone out of a dime. In fact, most of these trades turned out to be hugely profitable."

The indictment alleges Litvak misrepresented asking and selling prices, keeping the difference between the price paid by the buyer and the price paid to the seller for Jefferies. In other transactions, Litvak misrepresented to the buyer that bonds held in Jefferies' inventory were being offered for sale by a fictitious third-party seller, which allowed Litvak to charge the buyer an extra commission that Jefferies was not entitled to, authorities said.

"As most Americans tried to keep their heads above water during the financial crisis, Jesse Litvak is charged with trying to profit from the taxpayer-funded bailout known as TARP," said Special Inspector General for TARP Christy Romero. "The charges paint a picture of Litvak shamelessly lying to dupe the government into overpaying for mortgage securities with bailout funds."

The indictment charges Litvak with 11 counts of securities fraud, which carry up to 20 years in prison on each count, one count of TARP fraud, which carries a maximum term of imprisonment of 10 years, and four counts of making false statements, which each carry a maximum prison term of five years if convicted.

Associated Press

Source: http://hosted2.ap.org/APDEFAULT/f70471f764144b2fab526d39972d37b3/Article_2013-01-28-Trader-Fraud/id-65787e985cf545ae8039d91d9ea94499

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Complete list of winners at 19th annual SAG Awards

(AP) ? A complete list of winners at Sunday's 19th annual Screen Actors Guild Awards:

MOVIES:

Actor: Daniel Day-Lewis, "Lincoln"

Actress: Jennifer Lawrence, "Silver Linings Playbook"

Supporting actor: Tommy Lee Jones, "Lincoln"

Supporting actress: Anne Hathaway, "Les Miserables"

Cast: "Argo"

Stunt ensemble: "Skyfall"

___

TELEVISION:

Actor in a movie or miniseries: Kevin Costner "Hatfields & McCoys"

Actress in a movie or miniseries: Julianne Moore, "Game Change"

Actor in a drama series: Bryan Cranston, "Breaking Bad"

Actress in a drama series: Claire Danes, "Homeland"

Actor in a comedy series: Alec Baldwin, "30 Rock"

Actress in a comedy series: Tina Fey, "30 Rock"

Drama series cast: "Downton Abbey"

Comedy series cast: "Modern Family"

Stunt ensemble: "Game of Thrones"

___

Life Achievement: Dick Van Dyke

Associated Press

Source: http://hosted2.ap.org/APDEFAULT/4e67281c3f754d0696fbfdee0f3f1469/Article_2013-01-27-SAG%20Awards-List/id-0664329c7db541f38992c4cb1af7b75e

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Music Spotlight: Matt Hectorne & the Family Tree | Brite Winter Festival

Hanging around the green room below the Beachland Ballroom, Matt Hectorne seems at his most content talking church music and his Mississippi upbringings when the conversation comes to a halt and a smile breaks behind a grizzly beard. ??I?ll Fly Away,?? he points upstairs in approval to the Womack Family Band?s psychedelic rendition of the spiritual standard taking place on stage that?s echoing through the floor. In 20 minutes he?ll take the stage himself for the last time with Humble Home. In five months he?ll move to Nashville.

For a boy who grew up in a small suburb of Memphis immersed in a church of country and gospel vintage lore, a Southern homecoming marks the past year as a return to the roots. With a contributing cast of musicians he released two EPs, The Family Tree and Your Light My Dark, a collection of songs that were no doubt inspired by the way he paints his Episcopalian youth: Sunday bands with Elvis slick backs and sideburns, pedal steel and banjo players, running, screaming, dancing, and speaking in tongues.

?As soon as I started writing songs that style came naturally; the imagery, the Christian allegory,? Hectorne says of his early years. ?I started delving into outlaw country like Merle Haggard, Guy Clarke, Johnny Cash, Loretta Lynn. When I play now, it?s nothing I ever really think about any more. That?s just what comes out.?

The result was February?s Family Tree EP, written and recorded over an inspired two week span. Its spontaneous live recording added an immediacy to Hectorne?s antiqued Americana, a human quality that parallels the songs? themes of questioning and denouncing faith that ends with a stand-out bonus track of a sparse, arresting cover of Bruce Springsteen?s ?Downbound Train?.

?What I love about classic albums, when bands like the Byrds or the Animals would record live back in the day, is they just took everything off the floor, did a take and said that felt good, let?s just keep that,? he explains on producing the EP. ?It?s not so much that every song should be pristine; I think the idea of recording isn?t so much getting it perfect as getting it right for that moment. It should be a portrait of the time you were in.?

Hectorne spent the next months penning Your Light My Dark, an EP that expanded into moments of shimmering pop and choral sing-alongs. With the hushed harmonies of Nina DeRubertis becoming fully realized on the chanting hymnal ?(Will There Be a Time When I Will Not Be) Lost Without You? and the release of the stark black-and-white video for ?Coming Around?, Your Light My Dark is a project steeped in minimalism, an unembellished effort that finds beauty in subtlety.

?I never set out to make the simplest video or the simplest sounding recording. To me it?s just being honest and almost a necessity. I?m not necessarily a prolific musician; I learned my instrument to write songs and it?s all I know,? says Hectorne. ?But when you strip songs down, the only thing that stands up or holds anything together is the lyrics. You have no room for any other pretense. You have the song or you have nothing. ?

In late June, Hectorne will move to Nashville with a two week tour planned for this year and demos in the works that he hopes to turn into a full-length album to be released by early 2014. ?I love the hospitality of the South,? he says about the move. ?I love the dynamic and that?s where I want to be. I just feel like it?s the right time and I feel very good about it.?

Matt Hectorne & the Family Tree plays at the Market Avenue Wine Bar. Stream the Family Tree?s album?Your Light My Dark?on?Bandcamp?and keep up with them on?Facebook?and?Tumblr.

?



Source: http://www.britewinter.com/music-spotlight-matt-hectorne-the-family-tree/

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Monday, January 28, 2013

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Sunday, January 27, 2013

Disney says JJ Abrams to direct next 'Star Wars'

LOS ANGELES (AP) ? It's official. The force is with J.J. Abrams.

The Walt Disney Co. issued a statement Friday night confirming reports that had been circulating for two days that Abrams, Emmy-award-winning creator of TV's "Lost" and director of 2009's "Star Trek" movie, has been pegged to direct the seventh installment of the "Star Wars" franchise.

"J.J. is the perfect director to helm this," said Kathleen Kennedy, the movie's producer and president of Lucasfilm, which was acquired by Disney last month for $4.06 billion.

"Beyond having such great instincts as a filmmaker, he has an intuitive understanding of this franchise. He understands the essence of the Star Wars experience," Kennedy said in the statement.

The movie will have a script from "Toy Story 3" writer Michael Arndt and a 2015 release.

Lawrence Kasdan, who wrote "The Empire Strikes Back" and "Return of the Jedi" in the original trilogy, will work as a consultant on the new project.

Abrams has already headed the reboot of another storied space franchise, "Star Trek," for rival studio Paramount Pictures. The next installment in that series, "Star Trek: Into Darkness," is set to hit theaters May 17.

But he has long been known as a "Star Wars" devotee. Abrams spoke about the plot of the original "Star Wars" in the lecture series "TED Talks" in March 2007, and reportedly became enamored of "Lost" co-creator Damon Lindelof partly because Lindelof was wearing a "Star Wars" T-shirt when they first met.

In 2009, Abrams told the Los Angeles Times: "As a kid, 'Star Wars' was much more my thing than 'Star Trek' was."

In Friday night's statement he called it an "absolute honor" to get the job.

"I may be even more grateful to George Lucas now than I was as a kid," Abrams said.

Lucas himself said in the statement that "I've consistently been impressed with J.J. as a filmmaker and storyteller. He's an ideal choice to direct the new Star Wars film and the legacy couldn't be in better hands."

Source: http://news.yahoo.com/disney-says-jj-abrams-direct-next-star-wars-062821520.html

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Davos summit ends with warnings on global economy

DAVOS, Switzerland (AP) ? Top international financial officials wrapped up the World Economic Forum in the Swiss resort of Davos warning that much needs to be done to stabilize the world economy.

Despite relief that the euro, for all its struggles, remains intact and the U.S. has so far managed to get through a crucial budget hurdle, the International Monetary Fund's managing director Christine Lagarde urged world leaders to "not relax."

Lagarde said Saturday that the 17 European Union countries that use the euro have to follow through on steps to keep the troubles at banks from burdening governments.

And she said U.S. officials have to "indicate very promptly" how they're going to deal with their ongoing budget dispute between President Barack Obama and Republicans in Congress.

Source: http://news.yahoo.com/davos-summit-ends-warnings-global-economy-152248504--finance.html

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Reports: Exit locked at burned Bangladesh factory

DHAKA, Bangladesh (AP) ? An official says Bangladesh's government has ordered an investigation into allegations that the sole emergency exit was locked at a garment factory where a weekend fire killed seven female workers.

The fire Saturday at the Smart Export Garment Ltd. factory occurred just two months after a blaze killed 112 workers in another factory near the capital, raising questions about safety in Bangladesh's garment industry, which exports clothes to leading Western retailers. The gates of that factory were locked.

Government official Jahangir Kabir Nanak says an investigation has been ordered into the cause of Saturday's fire and allegations that the emergency exit was locked.

Doctors say most of the victims died from asphyxiation.

Source: http://news.yahoo.com/reports-exit-locked-burned-bangladesh-factory-074125331.html

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Saturday, January 26, 2013

Legal Commission meets in Lausanne | FIVB - Press release



Legal Commission meets in Lausanne

Lausanne, Switzerland, January 25, 2013 ? The FIVB Legal Commission completed their annual two-day meeting at the FIVB headquarters in Lausanne, Switzerland where they reviewed some of the FIVB?s key regulations.

The Commission gave a final review of the Disciplinary and General Regulations while also reviewing amendments to the Sports Regulations affecting cases of transfers?and change of federation of origin.

Modifications to the procedure of resolution between players, coaches and club disputes was also studied.

All proposals of the Legal Commission will be put forward to the FIVB Executive Committee, who will meet on the eve of the FIVB Board of Administration meeting on April 3, for approval.

A total of 10 FIVB Commission meetings are being held over the course of January with the Medical Commission meeting on Saturday and Sunday.



Source: http://www.fivb.org/viewPressRelease.asp?No=37448&Language=en

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Square COO quit after sex harassment accusation

SAN FRANCISCO (Reuters) - The chief operating officer for mobile payments company Square, Keith Rabois, abruptly resigned this week because an employee accused him of sexual harassment and demanded "millions of dollars" to stave off a potential lawsuit, Rabois said in a Friday blog post.

The revelation by Rabois, a well-known senior executive and active startup investor, caused a sensation in Silicon Valley and ignited a flurry of online chatter about Square, founded in 2009 by Twitter co-creator Jack Dorsey.

Rabois' case, which involved a same-sex relationship with a Square employee, follows another Silicon Valley workplace scandal eight months ago when Kleiner Perkins executive Ellen Pao alleged incidents of sexual harassment in a lawsuit against the high-powered venture capital firm for gender discrimination.

Kleiner has denied all of Pao's claims and the case remains in court.

In a lengthy Tumblr blog post, Rabois said he had been contacted by a New York attorney for his accuser, an unidentified male with whom he had a relationship beginning in 2010. Rabois, who recommended the man for a position at Square, said he was recently told his accuser would file a lawsuit alleging that their relationship was not consensual, and that Rabois did "horrible things," which Rabois did not spell out.

"I was told that only a payment of millions of dollars will make this go away, and that my career, my reputation, and my livelihood will be threatened if Square and I don't pay up," Rabois wrote.

Rabois, 43, flatly denied the allegations and pledged to defend himself.

"The relationship was welcome," Rabois wrote. "While I have certainly made mistakes, this threat feels like a shakedown, and I will defend myself to the full extent of the law."

A lawyer by training, Rabois detailed how he met his accuser through mutual friends. Several months after the meeting and after they had spent time together, Rabois said he recommended his friend to the company, which hired him. It is unclear whether the accuser still works at Square.

"I realize that continuing any physical relationship after he began working at Square was poor judgment on my part," he wrote, adding that the company did not know of the relationship until the recent lawsuit threat.

Dorsey, who accepted Rabois' resignation late on Thursday, declined to comment on Friday.

Attempts to reach Steve Berger, the lawyer representing the unnamed accuser, on Friday were unsuccessful.

Source: http://news.yahoo.com/square-coo-quit-sex-harassment-accusation-033103668--finance.html

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5 Obvious Goal Setting Mistakes You Must Avoid - by Dumb Little Man

Goal setting can get overwhelming.

To get the maximum results and to actually achieve your goals, you have to know what you're doing.

If you miss something important, or make an obvious mistake, it could mean significantly delaying your progress.

That's why I've written this article, where you'll discover 5 obvious goal setting mistakes you must avoid.

That is, if you want to achieve your goals.

This isn't rocket science. It isn't hard. It comes down to making progress.

Let's dive into the mistakes.


1. Not determining persuasive reasons for setting and reaching goals.

??Why am I doing this??

You need to define a clear and convincing answer for this before you even start listing down your goals.

Your answer will be your anchor to help you stay put and stay on the right track, especially when things get rough.

It will serve as your number one motivational factor. Look back on it often so you will be reminded why you?ve set a goal in the first place. If you fail to do so, you might lose the appetite to continue or even start on your goals.

2. Not realizing the benefits that come from reaching your goals.

You already know that you have a great reward waiting for you once you?ve reached your goal(s).

For example, you are aware that you can be healthier once you have obtained your aim of losing 10 pounds for each month of year 2013.

But, think of other benefits that may come along with your ?main? reward; things like, self-confidence, a great body, attractiveness, become an inspiration to other people, improved self-control, rejuvenated spirit, great eating habits, and so forth. List all good things that may happen to you or you can get from reaching each goal.

List as many as you can.?

The mere looking at that list can give you enough motivation to start and continue working on your goals. Review your list often so you will have a continuous push towards the end of your journey.

3. Not realizing the consequences of not reaching your goals.

Realizing and writing down all the benefits of achieving a goal is as vital as realizing the bad things that may happen if you fail or refuse to set goals.

This list, though it contains negative things that might happen, it can motivate you. For example, for your weight loss goal for 2013 you list down: hating yourself, disappointing your family, losing the confidence of friends, suffering a fatal disease, or dying young.

Make it as scary and as undesirable as possible, but factual.

Once you?ve realized that those are the consequences of not being successful in that particular goal, the scary feeling you may feel at first can turn into a strong desire to work on losing that 10 pounds every single month simply because you do not want those things to happen to you.

Also, include things you will miss if you do not set goals or fail to reach them. This list however, can have a negative impact on you. It can make you upset or depressed if you're not careful.

Study how negative things can create positive impact, because they do. This is like the principle behind converting stumbling blocks into stepping stones.

4. Not evaluating your level of readiness.?

Being ready is the first step to success.

You cannot win any competition, pass any exam, become rich, have a happy marriage, have a fit and healthy body, or reach any goal, if you are not prepared. In setting any goal, you need to determine how prepared you are physically, mentally, socially, emotionally, or financially.

Being emotionally prepared is the most important because even if you lack money, you lack support from family and friends, or you are physically ill, if your emotions and spirit are strong, and indestructible, you can surpass anything and do anything.

Be ready to be criticized, discouraged, mocked, or laughed at. Because when you are emotionally weak, your motivation may melt, your heart can be broken, and your spirit can shatter, which will make it impossible for you to be successful.

Also, you need to evaluate your strengths and weaknesses, your knowledge and skills, even the help and assistance available for you. Sort and list them all down.

This way you can have an idea of how prepared you are before ?going to a war.? ?Yes, working on your goals can be like a war and you cannot triumph over it unless you are prepared.

5. Not learning from both yours and other people?s mistakes and failures.

One smart way to avoid obstacles is by studying your route; things like puddles, stones, sharp or blind curves, debris, or rough and bumpy parts of the road.

The same principle applies in goal setting. Review your past failures and make sure you improve and do not repeat the things you did poorly. This is a great way of looking at and dealing with failure.

Instead of losing hope and quitting because you fail, convert that unpleasant experience and feeling into something productive and motivational.
? ?
Also, learn from other people?s mistakes or failures in setting goals. It?s wiser to know and avoid possible challenges because you heard and learned them from other people rather than messing up first and learning from it.

Source: http://www.dumblittleman.com/2013/01/5-obvious-goal-setting-mistakes-you.html

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Friday, January 25, 2013

Online Business and Social Media Program in NM ? New Mexico ...

Posted by Fahz on 2013/01/24

For our Western Evaluation Capacity Training course, I have come out initially with this idea for a program to teach NM residents to utilize internet resources to come out and/or promote their business. NM is rich with traditions, demanded items, crafts of different ethnic groups, and historical items. Due to time limitations and other opportunities, I never had a chance to fully develop this program beyond this Logic Model:

FahzyLogicSpec20120316.PDF

HomeBizLogic

If you have ideas and would like to collaborate, let me know.

Source: http://nmresource.wordpress.com/2013/01/24/onlinebusiness/

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Military has to decide which combat jobs for women

WASHINGTON (AP) ? The Pentagon's decision to lift the ban on women serving in combat presents a daunting challenge to top military leaders who now will have to decide which, if any, jobs they believe should be open only to men.

Defense Secretary Leon Panetta is expected to announce Thursday that more than 230,000 battlefront posts ? many in Army and Marine infantry units and in potentially elite commando jobs ? are now open to women. It will be up to the military service chiefs to recommend and defend whether women should be excluded from any of those more demanding and deadly positions, such as Navy SEALs or the Army's Delta Force.

The historic change, which was recommended by the Joint Chiefs of Staff, overturns a 1994 rule prohibiting women from being assigned to smaller ground combat units.

The change won't take place overnight: Service chiefs will have to develop plans for allowing women to seek the combat positions, a senior military official said. Some jobs may open as soon as this year, while assessments for others, such as special operations forces, may take longer. The services will have until January 2016 to make a case to that some positions should remain closed to women.

Officials briefed The Associated Press on the changes Wednesday on condition of anonymity so they could speak ahead of the official announcement.

There long has been opposition to putting women in combat, based on questions of whether they have the necessary strength and stamina for certain jobs, or whether their presence might hurt unit cohesion.

But as news of Panetta's expected order got out, many members of Congress, including the Senate Armed Services Committee chairman, Sen. Carl Levin, D-Mich., announced their support.

"It reflects the reality of 21st century military operations," Levin said.

Objections were few. Jerry Boykin, executive vice president of the Family Research Council, called the move "another social experiment" that will place unnecessary burdens on military commanders.

"While their focus must remain on winning the battles and protecting their troops, they will now have the distraction of having to provide some separation of the genders during fast moving and deadly situations," said Boykin, a retired Army lieutenant general. He noted that small units often are in sustained combat for extended periods of time under primal living conditions with no privacy.

Panetta's move comes in his final weeks as Pentagon chief and just days after President Barack Obama's inaugural speech in which he spoke passionately about equal rights for all. The new order expands the department's action of nearly a year ago to open about 14,500 combat positions to women, nearly all of them in the Army.

In addition to questions of strength and performance, there also have been suggestions that the American public would not tolerate large numbers of women being killed in war.

Under the 1994 Pentagon policy, women were prohibited from being assigned to ground combat units below the brigade level. A brigade is roughly 3,500 troops split into several battalions of about 800 soldiers each. Historically, brigades were based farther from the front lines, and they often included top command and support staff.

The necessities of combat in Iraq and Afghanistan, however, propelled women into jobs as medics, military police and intelligence officers that were sometimes attached ? but not formally assigned ? to battalions. So while a woman couldn't be assigned as an infantryman in a battalion going out on patrol, she could fly the helicopter supporting the unit, or move in to provide medical aid if troops were injured.

And these conflicts, where battlefield lines are blurred and insurgents can lurk around every corner, have made it almost impossible to keep women clear of combat.

Still, as recent surveys and experiences have shown, it will not be an easy transition. When the Marine Corps sought women to go through its tough infantry course last year, two volunteered and both failed to complete the course. And there may not be a wide clamoring from women for the more intense, dangerous and difficult jobs, including some infantry and commando positions.

Two lawsuits were filed last year challenging the Pentagon's ban on women serving in combat, adding pressure on officials to overturn the policy. And the military services have been studying the issue and surveying their forces to determine how it may affect performance and morale.

The Joint Chiefs have been meeting regularly on the matter and they unanimously agreed to send the recommendation to Panetta earlier this month.

A senior military official familiar with the discussions said the chiefs laid out three main principles to guide them as they move through the process. Those were to maintain America's effective fighting force, preserve military readiness and develop a process that would give all service members the best chance to succeed.

Women comprise about 14 percent of the 1.4 million active military personnel. More than 280,000 women have been sent to Iraq, Afghanistan or to jobs in neighboring nations in support of the wars. Of the more than 6,600 U.S. service members who have been killed, 152 have been women.

The senior military official said the military chiefs must report back to Panetta with their initial implementation plans by May 15.

___

AP National Security Writer Robert Burns and AP Broadcast reporter Sagar Meghani contributed to this report.

Source: http://news.yahoo.com/military-decide-combat-jobs-women-080645647.html

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Strange Exoplanet's 'Backwards' Orbit Explained by Extra Star, Planet

A perplexing alien planet locked in a "backwards" orbit around its parent star may finally be explained by the discovery of an extra planet and star near the oddball planetary system, scientists say.

The discovery is centered on the so-called "backwards" planet HAT-P-7b, which orbits a star 1,040 light-years from Earth in the constellation Cygnus. The planet, first spotted in 2008, has long defied explanation because of its orbit, which carries the world around its parent star in the opposite (or retrograde) direction of the star's spin.

Now, a Japan-led team of astronomers has found a second star and alien planet near the planet HAT-P-7b and its stellar parent. They used the Subaru Telescope Facility in Hilo, Hawaii, to make the discovery. Long-term gravitational interference from the newfound star and alien planet, which is a Jupiter-size world called HAT-P-7c, may be responsible for the strange retrograde orbit of HAT-P-7b, researchers said.

While the planets of Earth's solar system all orbit the sun in the same direction as the sun's spin, astronomers have observed retrograde planets circling distant stars. How these exoplanets got on such unusual paths has remained a mystery. The newfound planet and star near the HAT-P-7b planetary system could change that. [The Strangest Alien Planets (Gallery)]

"The current team thinks that the existence of the companion star (HAT-P-7B) and the newly confirmed outer planet (HAT-P-7c) are likely to play an important role in forming and maintaining the retrograde orbit of the inner planet (HAT-P-7b)," officials with the Subaru Telescope Facility explained in a statement today (Jan. 24). ?

The orbit of the newly discovered planet HAT-P-7c is located between the retrograde HAT-P-7b and the newfound star, the researchers explained. The newly discovered second star pulled the giant outer planet into a tilted orbit until its path started affecting the inner planet, HAT-P-7b, generating the latter's retrograde orbit, they added.

This sequence of gravitational dominos could account for the backward journeys of many retrograde extrasolar planets, Subaru observatory officials said. It also clears up a recent study that suggested the backwards planet and its parent star on their own could not explain the oddball orbit setup.

That 2012 study, by another researcher, determined that the gravitational push and pull between HAT-P-7b and its central star should prevent the?exoplanet?from maintaining its counterintuitive orbit.

The new study was led by astronomer Norio Narita, Yasuhiro Takahashi, Masayuki Kuzuhara, and Teruyuki Hirano of the National Astronomical Observatory of Japan and the University of Tokyo.

Follow Miriam Kramer on Twitter?@mirikramer?or SPACE.com?@Spacedotcom. We're also on Facebook?&?Google+.?

Copyright 2013 SPACE.com, a TechMediaNetwork company. All rights reserved. This material may not be published, broadcast, rewritten or redistributed.

Source: http://news.yahoo.com/strange-exoplanets-backwards-orbit-explained-extra-star-planet-114556224.html

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Thursday, January 24, 2013

Dustin Hoffman: what "The Graduate" taught me about directing

(Strong language in paragraph 22)

NEW YORK (TheWrap.com) - Three decades after Dustin Hoffman fired himself from his first directing job, the Oscar winner has finally made his first movie, an intimate tale of four retired musicians in a home filled with wise-cracking septuagenarians.

"Quartet," which stars revered British actors Maggie Smith and Michael Gambon, is an ode to both exuberance and old age, to pursuing your passion no matter your physical or mental state.

One moment you see Maggie Smith struggling to stand up, the next moment you hear jokes about Apricot Jam and "rumpy fumpy."

The film has already made $11 million at the box office in the United Kingdom, where it first opened, and rolls out nationwide in the U.S. this weekend.

It has put together two strong weekends at the domestic box office in limited release - and earned Smith a Golden Globe nomination for Best Actress in a musical or comedy.

For Hoffman, it was a revelation, a new experience in film for an actor who already has two Academy Awards and been nominated five other times. He is openly disdainful of "retirement," that being something for people who don't like their jobs.

TheWrap talked with Hoffman about the challenges of directing, how Hollywood mistreats actors and why he welcomes failure.

What brought you to this project?

It had something that resonated with me, something I knew about - not opera, but spending a lifetime performing. Unlike acting, opera singers have a limited shelf life. To still have the passion and the desire to do it, which I do about acting when I get good parts, but be forced to live in a retirement home. These people refuse to retire and that was enough to get me in there.

For the first time in three decades. You almost directed "Straight Time" in the late 1970s.

And I made the mistake of firing myself. I cast it, crewed it, took some months and started shooting in Folsom Prison. There was great pressure from the person at the studio I was doing it under. A friend of mine (Ulu Grosbad) wanted to take over, and I do think it's one of the better films I've made.

And then you never directed again. Why not?

I went on to develop more material. If you want to do what you want to do rather than just waiting for an angel to drop a script at your front doorstep ? that's why Robert Redford, Warren Beatty and other people of my generation developed things.

I developed two or three and I'd get to a point where frustration set in. I've always been bored hearing stories of projects that took an interminably long time. Clint Eastwood's "Unforgiven" took him 17 years. I'd put a project aside when a part came along, but that's six months out of your life even as an actor. The years kind of flew by.

Whatever other demons were delaying my re-entry, suddenly I was able to get a grip on it. My wife and agent have collaborated to push me over the edge.

Would you go back to one of those ideas you were developing it?

I'm taking a look at a couple of things I had put aside as we speak. I'm obviously quite proud of this film, and I'm trying to figure out how to direct something after I die. I don't know if Shirley MacLaine has a corner on that market or not, but that's how passionate I am.

This movie flitters in between moments of absurdist comedy and solemnity. How do you balance those two moods?

When I was a young actor, it was amazing how many times people asked, ?So what do you do, tragedy or comedy?' Arthur Miller told me people don't realize "Death of a Salesman" is a comedy. If you do it right, the character is so contradictory the audience laughs all the way through it. If you took the laughs out of "Rain Man," it's not "Rain Man." Mel Brooks said it best: If you see someone slip on a banana it's funny and you laugh. If you're the one that slips on a banana it's a tragedy.

You came into this with a few actors already attached, but how did you find all of the other people in the retirement home? I knew I had to hire real actual retired opera singers and musicians and was finally able to do with an extraordinary casting session. We scoured the U.K., Ireland, Scotland, and the answer to your question is that what none of us expected. These are real actual human beings whose phone had not rung for 30, 40 years until we gave them a job to be in this film. The wild card is that when we started shooting, they arrived at 6 a.m. and worked long, low-budget hours every single day on location. They worked with such passion and dedication that it enveloped all of us.

There's a woman who opens the movie, Patricia Loveland, who did not start acting until she was 60 and ended up in this. There had to be a lot of stories like that.

One out of the 50 people or so who were moved by this experience, Ronnie Hughes, is a trumpet player. Someone had seen him play at some small gig in some obscure fuck part of England and thought he was extraordinary. The movie was all live singing and the trumpet too. He has not lost his chops as they say.

How did those musicians influence your approach to the subject matter? Their lives in some ways resemble your story. I said to the main actors that we're all in our 70s here and we are all going to be working with people in their 70s, 80s and 90s.

These are not actors. I've asked them to not "act," and I will guide them as best as I can. We have to fit in with that. We know more than anyone or as much as anyone in our generation what it feels like to be at this stage of our career and life.

How did your acting experiences influence you as a director?

We all get labeled something because it's a lazy approach to defining someone. I was the difficult one, warren was the ladies man, Nicholson was the recreational drug user All of it to some degree was distorted. In my generation I guess what people never printed was that when I started making movies it was "The Graduate." I was almost 30 playing someone 21, and I didn't know how movies were done.

And Mike Nichols taught you how movies were made.

He did something I didn't know was out of the ordinary - a one-month rehearsal on a soundstage at Paramount. He worked with us as principles as you would on a play. You don't present the character on the first day as many actors have to do to get the job. We slowly started to build the characters and define scenes from that.

It's the very thing you're not allowed to do because studios feel it cost so much to make the movie that way. They're wrong. It's worth it rather than forcing the scenes on a day to day basis; the verities of filmmaking demand it.

I was guided by Nichols. God knows he wasn't criticized for being a perfectionist, but everyone behind the camera is a perfectionist or they lose their job.

How did Nichols compare to some of the other directors you worked with?

My second director was John Schlesinger, who did the same thing in a different way. We were in a room when he directed Voight and I and other principals and Waldo Salt sat in the corner with a tape recorder. He had us improvise every single scene for three weeks at least and Waldo would take the recording home, transcribe it and incorporate it into thing that was written. I believed this was the way movies were done. It was a shock to my system when I realized those were aberrations.

Were you able to adopt some of that rehearsal and improvisation for your movie?

We improvised all throughout the film. There were obstacles; there will always be obstacles, but we're not tied to the script word for word. Consequently some of great moments and dialogue just came out. When Maggie and Tom are in the church in this one scene. She says, "Why do we have to get old?" Tom paused and after a few he said, "Because that's what people do." That's one of the great lines in the film, and it came right out of this guy.

Maggie was the first actor attached to the project, right? She's had something of a late career renaissance.

Maggie personifies the soul of this movie. I read a London Times interview she had given years ago in her early 70s and she made it no secret she was in the midst of chemo and radiation. It had just floored her. Someone who had spent her lifetime at her craft said, "I don't want to do it; I have no passion for it. That's it, I'm giving up." A few years later she took a job and she has never stopped working since.

Do you see any irony in an iconic American actor making his first movie with a British production company and an all British cast?

I hadn't really thought of that. Actors aren't labeled by ethnicity. There's good acting and there's acting that isn't good. British actors had a training we didn't have with classics and Shakespeare, whereas American actors learned from Eugene O'Neill and Clifford Odets and Arthur Miller. A bridge was put between us that doesn't really exist today.

What I think is funny seems to be funny on both sides of the Atlantic. It is an American who directed it and British audiences are apparently filling up those theaters and continue to applaud at the end.

You mentioned it's found an audience in England and Australia. How nervous about are you about its financial performance in the United States?

I'm on a side of camera I haven't been before and it's embarrassing for me to have gone 40 years not knowing certain things.

Steven Spielberg told me years ago when I asked him about nerves that every film he start he pulls over on the first day and throws up. Greg Louganis won all these medals and I think his last dive was a basic dive and he smacked his forehead on the diving board. It was an extraordinary moment, and I've never forgotten it. It's a 10th of an inch whether you fail when you put yourself out there or succeed with a high number.

And Boston Celtics center Bill Russell famously vomited before games.

I was watching the Alabama-Notre Dame came on Monday. Alabama was up four touchdowns and its coach got into a huge argument with one of the referees. He was furious. After the game, they asked him, "Can you celebrate now?" He says, "Yeah, but in two days we start working for next year."

You're not doing it to suddenly get a crown and sit on the throne. You do it because there's no other way you choose to survive.

I don't understand retirement. The only way I can understand it is if you spend a lifetime doing what you would not call your work but just a job. I had that those first 12 years where I would keep looking at my watch wondering when I could take a cigarette break.

If you are one of the few of us who really love your work, there is no idea of retiring.

Source: http://news.yahoo.com/dustin-hoffman-graduate-taught-directing-010432899.html

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Chance finding reveals new control on blood vessels in developing brain

Jan. 24, 2013 ? Zhen Huang freely admits he was not interested in blood vessels four years ago when he was studying brain development in a fetal mouse.

Instead, he wanted to see how changing a particular gene in brain cells called glia would affect the growth of neurons.

The result was hemorrhage, caused by deteriorating veins and arteries, and it begged for explanation.

"It was a surprising finding," says Huang, an assistant professor of neuroscience and neurology at the University of Wisconsin-Madison. "I was mainly interested in the neurological aspect, how the brain develops and wires itself to prepare for all the wonderful things it does."

But chance favors the prepared mind, as Louis Pasteur said, and Huang knew he needed to follow up on the suggestion that glia, normally considered "helpers" for the neurons, would affect the growth of blood vessels. For one thing, blood flow is a big deal in the brain, says Huang, whose collaborators included Shang Ma, in the graduate program in cellular and molecular biology at UW-Madison. "We know the brain is very energy-intensive. Per unit of volume, it consumes 10 times as much oxygen as the rest of the body."

Although it makes intuitive sense that blood vessel development should be guided by neuronal development in some fashion, Huang spent years making sure he wasn't being mislead by his experiment. Now, he's satisfied himself, and his scientific reviewers, and the journal PLOS Biology has just published his study.

Glial cells in the nervous system establish a nurturing environment for neurons but do not carry signals. In particular, Huang looked at "radial glial cells," which also act as stem cells in creating new neurons. Radial glia extend from the inside of the brain to the outside, and also guide growing neurons to their final locations.

A standard way to find out what cells and genes do is to "knock out" specific genes, using a technology invented at UW-Madison by former professor Oliver Smithies (who shared the 2010 Nobel Prize for this discovery).

When Huang grew mice with a "knock out" mutation that blocked cell division among the radial glia, he expected to see abnormalities in the embryonic brain. But the major abnormality was completely unexpected: blood vessels that had already formed had collapsed.

New blood vessels in an embryo generally develop via a two-step process, first growing, and then stabilizing. "If the second step cannot be carried out, the vessels may already be formed, but the organ still cannot get its blood supply because the vessel will regress, or collapse," Huang says.

When blood vessels collapse, neurons start to die, says Huang. Some brain diseases, including Alzheimer's and hemorrhagic stroke, show a similar regression, and Huang says it's possible that the signaling mechanism that he experimentally blocked may play a role in these diseases as well.

Although any clinical treatment is years away, Huang is still basking in the thrill of basic discovery.

"We find that these progenitor and helper cells, the radial glia, regulate blood vessel development, and nobody has found that before." Huang says. "We used a mouse with alterations in genetics that regulate activity in these helper cells in the brain, and were very surprised to see that this had a drastic effect on blood vessel development. Previously it was always thought that these were two separate systems, now we know there is crosstalk between them. It's almost like a new field has opened up."

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The above story is reprinted from materials provided by University of Wisconsin-Madison. The original article was written by David Tenenbaum.

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Journal Reference:

  1. Shang Ma, Hyo Jun Kwon, Heidi Johng, Keling Zang, Zhen Huang. Radial Glial Neural Progenitors Regulate Nascent Brain Vascular Network Stabilization Via Inhibition of Wnt Signaling. PLoS Biology, 2013; 11 (1): e1001469 DOI: 10.1371/journal.pbio.1001469

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Source: http://feeds.sciencedaily.com/~r/sciencedaily/most_popular/~3/sUfC38d4lkw/130124150847.htm

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